FOXO1 and precursor B-cell acute lymphoblastic leukemia: A similar bimodal response to activation/inhibition of FOXO1 in the context of B-ALL has been reported previously and counterintuitively, while our RNA-sequencing data provided ample evidence that FOXO1 overexpression reduced MYC, MTORC1 and CCND3 activity, these functions were also suppressed by FOXO1 inhibition [43].