Other candidate tumour suppressor genes (TSG) in the region include GRIK2, implicated from an inherited mutation found in a case of childhood B-ALL carrying a 6q deletion [10], while loss of BACH2 and CCNC function have been associated with B- and T-ALL, respectively, in animal models [11, 12]. This evidence concerns the gene BACH2 and precursor B-cell acute lymphoblastic leukemia.