CEACAM5 and melanoma: Regarding CEACAM5 and the role of carcinoembryonic (CEA) related cell adhesion molecules (CEACAMs) 1, 5 and 6 in progression of solid tumours (such as colorectal, lung, melanoma, breast, liver) including pancreatic cancer is well established, and their expression varies between different tumour histological subtypes43–45.