Nevertheless, when beta cell responsiveness was dissected into its dynamic (φdynamic) and static (φstatic) components, as described by the oral minimal model, we observed a lower dynamic, static, and total insulin secretion in those with moderate and severe OSA (p < 0.0001, p = 0.007, p = 0.007, respectively) (Fig. 1, panels A–C). This evidence concerns the gene INS and obstructive sleep apnea syndrome.