In this cohort, we observed significant association with genes previously associated with FTD, such as GRN (P = 2.6 × 10−4; odds ratio = 3.6; 95%CI, 1.65–7.95) or ALS such as SOD1 (P = 3.9 × 10−4; odds ratio = 21.1; 95%CI, 1.15–383.3) (Fig. 3a), supporting its relevance. This evidence concerns the gene GRN and frontotemporal dementia.