In addition, TANs sustain tumor angiogenesis through the release of the pro‐angiogenic factors BV8 and MMP9 that activate VEGFA.[19] Furthermore, it is reported neutrophils recruited to sites of inflammation increase lymphangiogenesis by secreting VEGFA and VEGFD in the absence of B cells.[26] However, whether TANs are involved in tumor lymphangiogenesis is unknown. This evidence concerns the gene VEGFA and neoplasm.