To our knowledge, no studies have looked into the polymorphism of the genes RASGRP1, NFkB, CHL1, MARCH3, PDGFD, MAST3, EPS15L1, C1QTNF3, CD46, COX18, NEURL1, PPIE, and PTX3 and its relatedness to mastitis in cattle. This evidence concerns the gene COX18 and mastitis.