IL10 and malaria: In the subgroup analysis based on the method for the IL-10′s quantification, increased IL-10 levels were observed in patients with severe malaria than in those with uncomplicated malaria among studies that used an ELISA for the IL-10′s quantification; however, no difference in the IL-10 levels between patients with severe malaria and those with uncomplicated malaria was observed among studies that used a bead-based assay for the IL-10′s quantification.