STX2 and hemolytic-uremic syndrome: Stx2 can also induce the deposition of complement in red blood cells (RBCs), the release of hemoglobin and LDH (a marker of intravascular hemolysis) in STEC-HUS patients [19], and the release of in vitro complement-coated RBC-derived microvesicles, thereby inducing complement-mediated hemolysis.