SCN2A and neuroblastoma: Previously, Schweitz and co-authors found that RpII isolated from H. magnifica (=H. paumotensis) slowed down the inactivation of tetrodoxin-sensitive NaV currents expressed by neuroblastoma cells (NIE-115) and tetrodotoxin-resistant NaV currents in rat skeletal muscle tissue myoblasts [27] The results of Kalina et al. [168] confirmed that δ-SHTX-Hcr1f (=RpII) activated NaV1.2, the major subtype of channels expressed by neuroblastoma cells.