In males, pathways associated with adherens junction, type II diabetes mellitus, and arrhythmogenic right ventricular cardiomyopathy were significantly altered by Pb exposure, while in females, we observed differential expression of pathways related to phosphatidylinositol signaling, ABC transporters, proteasome, and Toll-like receptor signaling [57,58]. The gene discussed is ABCG2; the disease is Arrhythmogenic right ventricular dysplasia.