Additionally, the Angiopoietin-1 level was elevated in vitreous samples from PDR patients (184.01±391.08 pg/ml), when compared to control (32.48±47.51 pg/ml; p = 0.005) or DM samples (25.39±36.92 pg/ml; p = 0.013). The gene discussed is ANGPT1; the disease is diabetes mellitus.