Pregnant women with type 1 diabetes (T1D) are advised to aim for target glucose levels of 3.5–7.8 mmol/L for at least 70% of the day.1 Most women experience difficulties attaining these targets.2,3 Alongside challenges calculating carbohydrates and determining insulin dosages, physiological changes result in periods of insulin sensitivity in early pregnancy followed by increasing insulin resistance as pregnancy progresses.4 To help optimize glycemic management in pregnancy, guidelines recommend that women receive input and support from joint diabetes/antenatal teams every 1–2 weeks.5 This evidence concerns the gene INS and diabetes mellitus.