TNF and polycystic ovary syndrome: Zhao et al. reported the anti-inflammatory effect presented by hUC-MSCs specifically on the granulosa cells in the follicular fluid of the PCOS patients, and it was discovered that tumor necrosis factor alpha (TNF-α) and interferon gamma (IFN-γ) were significantly decreased and that IL-10 levels were upregulated in the PCOS patients [9].