IGHE and Increased total eosinophil count: The first report of this association involved a 50‐year‐old smoker with COPD who presented with features of an exacerbation and was subsequently diagnosed with ABPA on the basis of positive Aspergillus skin tests (both Type I and III), elevated total serum IgE, Aspergillus specific IgE and IgG, eosinophilia and a positive sputum culture for A. fumigatus [123].