CASP3 and lung adenocarcinoma: Preventing cell propagation at concentrations above 10 mM, inducing the apoptosis process through the upregulation of Bax/Bcl-2, inducing cell apoptosis due to increasing caspase-3 expression, suppressing the adhesion of lung adenocarcinoma by acting on VASP thereby influencing cell migration as well as tumor metastasis are the other applications of ICRN.