Preventing cell propagation at concentrations above 10 mM, inducing the apoptosis process through the upregulation of Bax/Bcl-2, inducing cell apoptosis due to increasing caspase-3 expression, suppressing the adhesion of lung adenocarcinoma by acting on VASP thereby influencing cell migration as well as tumor metastasis are the other applications of ICRN. This evidence concerns the gene CASP3 and neoplasm.