AKT1 and esophageal squamous cell carcinoma: Other studies have explored the expression of FGFR2 and its upstream regulator miR-671-5p in ESCC, showing an association between higher levels of FGFR2 and lower levels of miR-671-5p; high levels of FGFR2 induce the progression of ESCC due to the activation of the ERK and AKT pathways, while high levels of miR-671-5p induce the reduced expression of FGFR2 and the inhibition of ESCC progression [72].