In this gastric adenocarcinoma cohort from TCGA database, there were no significant differences of OS between overexpression and low expression of AKR1B10 in whole population; however, in the subgroup analysis, the survival outcome in difference races is a little different, better OS was mentioned in Asian patients with low expression of AKR1B10 compared to Asian patients with overexpression of AKR1B10. This evidence concerns the gene AKR1B10 and gastric adenocarcinoma.