OIP5 and esophageal squamous cell carcinoma: Firstly, ESC-410 and KYSE-150 ESCC cell lines were selected and divided into three groups: the control group (sh-NC), silenced-OIP5 gene group (sh-OIP5), and silenced-OIP5 group with exogenous overexpression of OIP5 (sh-OIP5 + OIP5).