OIP5 and neoplasm: The expression level of OIP5 was statistically significantly associated with tumor size (p = 0.026), T stage (p < 0.001), N stage (p < 0.011), and clinical stage (p < 0.001) in esophageal squamous cell carcinoma tissue, and no statistically significant difference was found between OIP5 expression and sex, age, M stage, and pathological grade (see Table 3).