On the other hand, no significant differences were detected concerning the association of the MEFV exon 2 methylation% and the pyrin level with genotyping among FMF patients, except the MEFV exon 2 methylation% of homozygous M694I (37.205 ± 6.6), which was significantly higher than homozygous M694V (22.48 ± 5.6) and M680I (9.88 ± 1.2) (p = 0.028), Table 3. The gene discussed is MEFV; the disease is familial Mediterranean fever.