Analysis of activated caspase 8 protein indicated an increase only in the sample of CIMVs-TRAIL (6.46 ± 0.8%) (n = 3, *** p < 0.001), but not the rest of the cancer cells cultured with native CIMVs (3.7 ± 0.4%), CIMVs-BFP (3.5 ± 0.7%) or without treatment (3.3 ± 0.2%). The gene discussed is TNFSF10; the disease is cancer.