Interestingly, the mRNA level of the BCL-2 gene in the tumor sample injected with native CIMVs was increased by 1.4 (n = 5, **** p < 0.0001), while the mRNA level of the BAX gene remained unchanged, the BAX/BCL-2 ratio was 0.7 (Figure 5). This evidence concerns the gene BCL2 and neoplasm.