After 72 h, the tumor cell viability according to the level of annexin remained reduced in the CIMV-TRAIL sample (85.0 ± 0.7% of alive cells) (n = 3, **** p < 0.0001) compared to native CIMVs (90.9 ± 0.3% of alive cells), CIMVs-BFP (90.2 ± 0.2% of alive cells) and native tumor cells (89.2 ± 0.1% of alive cells). Here, TNFSF10 is linked to neoplasm.