The overexpression of FOXM1 and CENPF in prostate cancer have been linked to the loss of microRNAs such as miR-101 and miR-27a, to the synergistic cancer induction through the upregulation of PI3K and MAPK signaling pathways, and to the poor prognosis prediction of cancer patients [50]. The gene discussed is FOXM1; the disease is prostate cancer.