NR4A3 (Nuclear receptor subfamily 4 group A member 3) is a tumor-suppressive gene with p53-dependent and -independent functions, which is a direct transcriptional target of p53 and related to cell proliferation, migration, and apoptosis [152], and elevating the intracellular levels of reactive oxygen species [153]. The gene discussed is ENSG00000279284; the disease is neoplasm.