Moreover, FOXF1 is also co-expressed in the CCP of the LC RNA-Seq datasets, along with seven of the most frequently dysregulated TFs (FOXM1, SOX17, TAL1, TCF21, TBX4, LMO2, and KLF2), suggesting its importance as a regulator of gene expression during lung cancer progression. This evidence concerns the gene TBX4 and lung cancer.