Furthermore, thirty-eight unique LC DEGs have experimental evidence of their association with cancer and DEGs related to the positive regulation of gene expression, cell division, growth, adhesion, proliferation, and differentiation, as well as TGF-β, metabolic, and BMP signaling pathways, and among all of them are five of the most frequent TFs (SOX17, NR4A3, MYBL2, DLX5, and KLF4) (Table S1). Here, KLF4 is linked to cancer.