HIF1A and alcohol dependence: In a study evaluating the gene expression change after 30 h cisplatin exposure, downregulated DEGs were associated with several KEGG pathways such as ‘systemic lupus erythematosus’, ‘alcoholism’, ‘viral carcinogenesis’, ‘PI3K-Akt signaling pathway’, ‘Rap1 signaling pathway’, and ‘HIF-1 signaling pathway’; which are in accord with our data (Supplementary Table S2).