MSCs are attracted to the tumor microenvironment through a chemotactic gradient comprised of soluble factors that include growth factors (e.g., TGF-β, EGF, PDGF, SCF, HGF, IGF-1 y GF, βFGF, HIF1α y VEGF) and some chemokine ligands (e.g., CCL2, CCL5, CCL22 y SDF-1α) secreted by tumoral cells [8,9,10,11,12,13,14,15,16,17]. Here, TGFB1 is linked to neoplasm.