PRKCD and Anxiety: Neurons expressing Prkcd have been shown to be suppressed by conditioned stimuli predicting an aversive stimulus (Haubensak et al., 2010), to modulate anxiety (Botta et al., 2015; Cai et al., 2014; Griessner et al., 2021), and to suppress food intake associated with either satiety or illness (Cai et al., 2014).