Activation of HIF‐1α triggers the transcription of genes involved in cancer (Miroshnikova et al., 2016) and immunity (Palazon et al., 2014), including cytokines IL8, IL6, ANGPTL4, VEGF and PDGF, which are commonly observed in SASP (Coppe et al., 2010; Zhang et al., 2012; Maxwell et al., 2007; Liu et al., 2009; Yoshida et al., 2006). This evidence concerns the gene CXCL8 and cancer.