However, the expression of CD161 in Head and Neck squamous cell carcinoma (HNSC), Lung adenocarcinoma (LUAD), Uterine Carcinosarcoma (UCS), Lung squamous cell carcinoma (LUSC), Bladder Urothelial Carcinoma (BLCA) was lower than normal tissues. The gene discussed is KLRB1; the disease is squamous cell lung carcinoma.