These potential target genes were placed in the Metascape for KEGG pathway analysis, and 20 significant pathways that may be regulated by HQHG in the treatment of ITP were identified, including pathways in cancer, lipid and atherosclerosis, endocrine resistance, human cytomegalovirus infection, hepatitis B, microRNAs in cancer, AGE-RAGE signaling pathway in diabetic complications, HIF-1 signaling pathway, and TNF signaling pathway. The gene discussed is RENBP; the disease is atherosclerosis.