LGR5 and gastric adenocarcinoma: However, in this study, we found that Lgr5 was significantly upregulated, but DCLK1 was significantly downregulated in early-stage STAD (Supplementary Table S3); moreover, DCLK1 was one of the mRNAs-OS (Supplementary Table S5), though it was not in the 9-mRNA prognostic model of this premature stage.