DACH1 and idiopathic membranous glomerulonephritis: Immunohistochemical staining of DACH1 proteins in human renal biopsies of immunoglobulin A nephropathy (IgAN) and idiopathic membranous nephropathy (IMN) patients show significantly decreased eGFR with declining DACH1, and significantly increased urinary protein in IMN with increasing DACH1 [77].