LGR5 and intestinal neoplasm: Interestingly, when using the stem cell index of intestinal tumor[24] to map our single cell transcriptome data, we found that irradiated cells (including [P], [B], [S], and [R]) were relatively more enriched toward “regenerative stem cells” (RSCs) rather than the classical LGR5+ crypt‐base columnar cells (CBCs) (Figure 5F,G).