BRCA1 and ovarian carcinoma: BRCA1, as an antioncogene, was genetically predisposed to breast and ovarian cancer cells; thus, it could be used for characterizing and screening patients against these two cancer types.[135a] Under optimal conditions, BRCA1 could be detected in a wide range from 0.01 to 15 ng mL−1 and with a detection limit of 4.86 pg mL−1.