For patients who had lymph node metastases with Ki-67 index < 2.85%, Tg expression > 75% was associated with longer RFS (153 months) compared to those having lymph node metastases expressing Tg 0–75% (130 months) (p = 0.019). This evidence concerns the gene MKI67 and metastatic malignant neoplasm in the lymph nodes.