By contrast, selective TF gene dependencies in Ewing sarcoma were transcriptional repressors, including the known dependencies BCL11B and ZEB2 (refs. 36, 37), which are activated by EWS–FLI, and the previously uncharacterized dependency ETV6 (Fig. 1a and Extended Data Fig. 1a). The gene discussed is ETV6; the disease is Ewing sarcoma.