Interestingly, while absent from the 215-gene list, the CLL-associated marker CD5 was overexpressed in RS versus DLBCL (2.4-fold; FDR = 2.13e−3) and highCLL-derived versus DLBCL-like RS (2.3-fold; FDR = 0.01). The gene discussed is CD5; the disease is B-cell chronic lymphocytic leukemia.