Interestingly, Silencing the expression of plexin-A2 in glioblastoma-derived cell lines expressing mutated P53 such as U373MG, U118MG or T98G cells [22] failed to inhibit cell proliferation (Figs. S1C & S1D) even though these cells do express plexin-A2 receptors (Fig. S1G). Here, TP53 is linked to glioblastoma.