RPS6 and neoplasm: Thus, while a modest increase in c-Myc alters the fate of neonatal hepatocytes in ΔS6 livers by preserving hepatocyte viability and eliminating the need for ΔS6 livers to regenerate, it is unable to overcome all of the derangements caused by Rps6 insufficiency and fails to prevent liver overgrowth or tumor development as mice age.