In the current study, besides the findings on BPA regulate LTP and LTD pathways, some other significantly differentially enriched pathways such as GnRH signaling pathway, Glutamatergic synapse pathway, Serotonergic synapse pathway, Neurotrophin signaling pathway, Glutamatergic synapse pathway, MAPK pathway might take part in the BPA mediated learning and memory impairment. Here, BDNF is linked to memory impairment.