In case the repeated mention of malaria causes confusion, the evolutionary selection for G6PD deficiency has nothing to do with the availability of 8-aminoquinoline drugs in the last half century, but instead should have to do with conferring resistance to Plasmodium falciparum infection over thousands of years, possibly through the increased phagocytosis of infected erythrocytes that are G6PD deficient [123]. The gene discussed is G6PD; the disease is G6PD deficiency.