INS and type 2 diabetes mellitus: To identify regulators of insulin secretion that may contribute to T2D, we generated RNA-Seq data from the large Lund University Diabetes Centre (LUDC) pancreatic islet cohort, comprising islets from a total of 309 donors (Supplemental Table 1; supplemental material available online with this article; https://doi.org/10.1172/JCI163612DS1).