Results showed that the protein levels of N-cadherin, Vimentin, Slug, p-HER2, p-EGFR, p-ERK1/2, MMP9 and MMP14 increased significantly in PLC/PRF-5LL−37 xenograft tumor; while significantly decreased in PLC/PRF-5LL−37 xenograft receiving si-LL-37 treatment (Figure 4a). This evidence concerns the gene SNAI2 and neoplasm.