This contrasted other ROs derived from CRB1‐related RP patients with (i) homozygous missense c.3122T>C, p.(Met1041Thr) variants and (ii) compound heterozygous nonsense c.2983G>T, p.(Glu995*) and missense c.1892A>G, p.(Tyr631Cys) variants, both of which showed correct localisation of Crumbs cell polarity complex proteins, including MPP5. This evidence concerns the gene PALS1 and retinitis pigmentosa 1.