BMP7 and major depressive disorder: Nevertheless, we identified an important overlap of positive association of 4 (rs2522833/PCLO, rs2715147/PCLO, rs9416742/BICC1, and rs999845/BICC1) and 1 (rs6127921/BMP7) variants between candidate and GWAS studies in MDD susceptibility and antidepressant response, respectively.