Interestingly, we observed variants of FKBP5 and HTR2A genes are being commercially utilized for diagnostic application in MDD gene panels (Rubinstein et al., 2013), and the replication of variants in these genes, rs1360780/FKBP5 (PPV = 0.53), rs4713916/FKBP5 (PPV = 0.53), and rs6311/HTR2A (PPV = 0.54), are demonstrated in our analysis. The gene discussed is HTR2A; the disease is major depressive disorder.