CD8A and vitiligo: 2010). CXCL9 and CXCL10 in vitiligo lesions target chemotactic CD8+ T lymphocytes to migrate towards the epidermis by binding to CXCR3 (Strassner et al. 2017). With elevated levels of chemokines CXCL9 and CXCL10 in the epidermis, CTLs undergo chemotaxis induced by chemokines and migrate from the vasculature to the epidermis, initiating specific cytotoxic effects by binding specifically to melanocytes and thus leading to melanocyte destruction and occurrence of white spots (Yang et al. 2018).