DDX60 and viral infectious disease: Type I IFNs induce DExD/H-Box helicase 60 (DDX60) as demonstrated by viral infection-induced gene microarray analysis in human dendritic cells [4]; DDX60 is an uncharacterized DEXD/H-box RNA helicase, similar to S. cerevisiae Ski2, a protein complex required for cytoplasmic RNA integrity.