However, in patients with moderate severity of ME/CFS median (IQR), IL-6 level was 4.5 (5.7–2) pg/ml, TNF-α–58 (123–32) pg/ml, IL-12–13.8 (16.4 –7.4) pg/ml and IL-10 level was 12.4 (25–6.7) pg/ml (Fig. 7). Here, TNF is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.