Tables 1, 2, 3 and 4 shows that univariate analysis revealed several factors were related to ICP (P < 0.10), such as BMI, diastolic blood pressure, gravidity, parity, mode of delivery, gestational days, infant weight, infant length, Apgar score, HDP, hyperlipemia, preterm birth, GDM, anemia during pregnancy, thrombocytopenia, premature rupture of membranes, fetal growth retardation and hepatitis B carriers. The incidence of other factors was not significantly different between the two groups (P > 0.10). This evidence concerns the gene PPIB and hepatitis A virus infection.