FAT1 and acute lymphoblastic leukemia: Investigating RNA-seq based transcriptome data from a T-ALL cohort of n = 83 adult patients we confirmed FAT1 overexpression in 53% of T-ALLs (FAT1pos, n = 45, median TPM 155, range 36–1368; Fig. 1a), whereas 47% of patients had very low/negative FAT1 expression (FAT1neg, n = 38, median TPM 0.5, range 0–27; Fig. 1a).