KIF7 and multiple epiphyseal dysplasia, Al-Gazali type: Of note, biallelic KIF7 variants can cause Al-Gazali-Bakalinova syndrome, which has a prominent skeletal phenotype including epiphyseal dysplasia, pectus deformities, hip dislocation, genu valgum, and prominent joints, and heterozygous variants in KIF7 have been reported in idiopathic scoliosis, supporting a role for KIF7 in skeletal development36,37.