When the angle between two arrows is small, the associated variables are highly correlated: for example, SeptiScore is correlated with SeptiCyte Band as would be expected, and is also correlated with other clinical variables that are elevated in the sepsis phenotype or in patients admitted to the ICU, such as C-reactive protein (CRP), D-dimer, interleukin-6 (IL-6), procalcitonin (PCT), and indicators of the systemic inflammatory response syndrome (SIRS). This evidence concerns the gene CRP and systemic inflammatory response syndrome.