Further, although the core SWI/SNF subunit SMARCA4 was expressed in almost all primary stem and non-stem tumor cells (Supplementary Fig. 1b), nuclear SMARCD3 expression was upregulated within freshly isolated primary KPf/fC CD133+ tumor cells, consistent with a role in the stem cell compartment (Fig. 1f, Supplementary Fig. 1c, d); CD133 is a cell surface marker commonly used to assess or isolate tumor stem cells by FACS9. Here, SMARCA4 is linked to neoplasm.