EPCAM and neoplasm: While each PDX sample was transduced equivalently at t = 0 (Fig. 3k, left and Supplementary Fig. 3g), the relative frequency and total number of GFP + EpCAM+ tumor cells were reduced by 2–50-fold in shSmarcd3 tumors at endpoint (Fig. 3k, middle and Supplementary Fig. 3g).